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Ketoacidosis in Cats

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Overview:

Diabetic ketoacidosis (DKA) is a life threatening complication of uncontrolled diabetes caused by a lack, or insufficient amount of insulin. This means glucose is unable to be used by the body for energy.  The body begins to search for alternate supplies of energy & begins to break down fat. When fat is broken down (metabolised) into fatty acids, waste products known as ketones (also known as ketone bodies) are produced & accumulate in the bloodstream. This causes the blood to become too acidic (acidosis).

The body will try to get rid of the ketones by excreting them into the urine, which causes increased urine output & increased thirst.

What causes ketoacidosis in cats?

There are several possible causes including;

  • Undiagnosed diabetes
  • Insufficient insulin
  • Missed insulin
  • Not enough food
  • Illness & or infections (especially of the urinary tract)
  • Obesity
  • Stress
  • Surgery
  • Idiopathic (no known cause)

What are the symptoms of ketoacidosis?

How is ketoacidosis diagnosed?

Your veterinarian will perform a complete physical examination from you & obtain a medical history. Some tests he may wish to perform include;

How is ketoacidosis treated?

Treatment depends on the severity of the condition. In mild cases, where your cat is still bright & alert home therapy may be all that is necessary. Regular monitoring of blood glucose levels should be performed.

In more serious cases, treatment includes;

  • Intravenous fluids & electrolytes  to treat  & correct dehydration & electrolyte imbalance (possibly supplementing with electrolytes such as sodium, potassium and chloride). This also dilutes glucose & acid levels.

  • Frequent administration of short-acting insulin to lower blood sugar levels.

  • Where possible, find out the cause (such as infection) of ketoacidosis & treat.

  • Regular monitoring of blood glucose, blood chemistry, electrolytes & urine for ketones.

  • Once the cat is stable (eating, hydrated, no vomiting etc), your veterinarian will change to a long-acting or intermediate-acting insulin. [2]

 

References:

[1] Cat Health Encyclopedia (P.262)- Edited by Dr. Lowell Ackermann.

[2] The Feline Patient - Essentials of Diagnosis & Treatment (P168) - Gary D. Norsworthy, Mitchell A. Crystal, Sharon K. Fooshee, Larry P. Tilley.

Please note:

The medical articles on this site have not been written by a veterinarian & should not be considered a replacement for a veterinarian visit. The articles are provided for informative purposes only.

Always seek immediate veterinary advice for any problems (health or behavioral) in your pets. 

While great care has been made in the creation of these articles, we cannot guarantee the accuracy or omissions on these pages. If in any doubt whatsoever, seek professional medical advice. 



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