About: Anaplasmosis is a tick-borne infection caused by intracellular bacterium Anaplasma phagocytophilum which takes up residence in the white blood cells of cats and other warm-blooded mammals.
Transmission: Ticks spread the bacteria when they feed on an infected animal. Bacteria in the host blood are ingested and make their way to the salivary glands of the tick. From there into the next host when the tick feeds on a blood meal.
Symptoms: Cats are often asymptomatic to anaplasmosis. When symptoms do present they include loss of appetite, fever, lethargy, and lameness.
Diagnosis: Baseline tests including complete physical examination and medical history, blood count, biochemical profile and urinalysis. Polymerase chain reaction (PCR) can diagnose infection.
Treatment: Mildly affected cats may require no treatment at all. Antibiotics for symptomatic cats.
Formerly known as Ehrlichiosis, Anaplasmosis is a tick-borne disease spread by ticks of the Ixodes genus. It is caused by the intracellular bacterium Anaplasma phagocytophilum. As one can guess, an intracellular bacterium lives in certain cells, and A. phagocytophilum takes up residence in the white blood cells, specifically granulocytes. These cells are responsible for fighting infection.
Anaplasma phagocytophilum infects humans and a wide range of animals including cats and dogs and has been detected in the following countries; United States, Sweden, Finland, Poland, Switzerland, Germany, Italy and Spain. In the United States, it is endemic in the upper Midwest, East, and Northeast regions as well as the western coastal regions. Infection occurs most often from spring to autumn. Cats who have had exposure to A. phagocytophilum may have a co-infection with other tick-borne pathogens.
A. phagocytophilum enter the tick gut when it feeds on the blood of an infected animal and from there, it migrates to the salivary glands and is secreted when the tick feeds on the next host. White-tailed deer, raccoon, white-footed mouse and the grey squirrel are important reservoirs of the disease. The tick must feed for 24 hours or more for transmission to occur. Cats who roam outdoors in rural areas are at greatest risk of infection.
Blood transfusion is another possible mode of infection.
It can take 1-2 weeks for symptoms to develop after a bite. Most infections are subclinical, or mind and non-specific which may include the following: